Cushing's Disease, also known as hyperadrenocorticism, is one of the most common endocrine disorders. Cushing's Disease occurs when the adrenal gland produces excessive cortisol, which is a natural steroid hormone. It most often affects older dogs and may be caused by a lesion in the pituitary gland at the base of the brain or, less frequently, when one of the adrenal glands has a tumor which excretes cortisol. There are certain breeds which are more prone to Cushing's Disease, including Beagles, Boston Terriers, Boxers, Dachshunds, and Poodles.
Detecting Cushing's Disease can sometimes be difficult as the symptoms often appear to be connected with the normal aging process or with other conditions. Symptoms may include the following: hair loss; high blood pressure; protruding, sagging abdomen; increased appetite; increased thirst; increased urination; muscle weakness; nervous system disorder; panting; and skin lumps and discoloring. A series of blood tests are needed to diagnose Cushing's Disease. Other disorders can result if this disorder is left untreated, including congestive heart failure, diabetes, hypothyroidism, liver and kidney failure, and infections of the bladder, ears, eyes, gums and skin. |